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Best Clinical Skincare Products for Melasma, Dark Spots, Hyperpigmentation, Discoloration, Sun Damage & Post Inflammatory Hyperpigmentation (PIH)

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Hello all! My background as a clinical esthetician, cosmetic chemist, academic dermatology and clinical skincare researcher is applicable on this topic. But here's what really matters…I'm a perimenopausal, 40 something y/o with a history of melasma a...
 
Erica Alexis profile picture
Game changing ingredient (thiamidol) for those of us with hormone-induced melasma, sun-induced pigmentation, & post inflammatory hyperpigmentation from acne & other skin injuries. Personal Fav!
Radiant Tone | Dark Spots
 
Erica Alexis profile picture
Excellent, mid price rage, derm created product that combines tranexamic acid, mandelic acid, kojic acid, glutathione, niacinamide and more ingredients for a truly comprehensive pigment inhibition product!
Remedy Advanced Dark Spot Serum with Kojic Acid ...
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Erica Alexis profile picture
Novel combination ingredient product that includes KT 939, tranexamic acid, alpha arbutin, niacinamide and more!
Level Serum - Hyperpigmentation Treatment
 
Erica Alexis profile picture
Popular, gentle serum of alpha arbutin, kojic acid and licorice root. Great starter for sensitive skin types.
Mae Love Fade Away Brightening Serum
 
Erica Alexis profile picture
Budget serum that includes 3% Cetyl Tranexamate Mesylate (form of tranexamic acid with better penetration into skin) & 4% niacinamide. Great starter serum to improve skin tone.
Good Molecules Discoloration Correcting Serum 30 ml
 
Erica Alexis profile picture
Affordable 5% tranexamic acid serum with kojic acid, niacinamide and licorice root. Solid formulation for a fair price.
Naturium Tranexamic Topical Acid 5%
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Erica Alexis profile picture
Little pricier, high quality 3% tranexamic acid serum that includes niacinamide, bakuchiol (natural retinoid-like ingredient) & antioxidants.
Paula's Choice CLINICAL Discoloration Repair
 
Erica Alexis profile picture
Great serum for chemical peel preparation 2-6 weeks pre procedure. Includes tranexamic acid, niacinamide, granactive retinoids, azaleic and kojic acids.
Platinum Skin Care Fade Bright Skin Lightening Gel - Pigmentation Treatment
 
Erica Alexis profile picture
Comprehensive, derm created system that includes 3 products containing various combinations of tranexamic acid, glycolic & lactic acids, alpha arbutin, glutathione, vitamin C, ceramides & peptides. a bit pricier but one stop shopping for disc...
Pillow Talk Major Fade Solution System
 
Erica Alexis profile picture
Same game changing ingredient (thiamidol) and company as Eucerin Radiant Tone! Just provides a slightly lower price point.
NIVEA, Serum, Luminous 630 Anti-Age & Dark Spot 2-in-1, ...
 
Erica Alexis profile picture
Azaleic acid acts as both an exfoliant and targets pigmentation especially for those with rosacea and acne, intolerant to stronger acids.
Naturium Azelaic Acid Derivative Complex 10% for Uneven Skin Tone
 
Erica Alexis profile picture
Pricey, derm created product with a cult following. Product includes salicylic acid, ascorbic acid (vitamin C), and kojic acid for gentle exfoliation and brightening. This works but you do pay more for the results.
Coleman Compound Brightening Pads
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Erica Alexis profile picture
Pricey, derm created product with a cult following that includes salicylic acid, ascorbic acid (vitamin C), and kojic acid for gentle exfoliation and brightening. Same as pads just a different delivery system for dry skin types.
Coleman Cosmetic Cream
 
Erica Alexis profile picture
Direct-to -you, derm formulated, customized cream that requires an online physician consultation and prescription (super quick & easy!). This product can include 12% hydroquinone (HQ), the gold standard for hyperpigmentation that can have side ef...
The Spot Cream | $36/mo | Dark Spots & Melasma
 
Erica Alexis profile picture
Classic, popular serum with tranexamic acid, niacinamide, azaleic and kojic acids. Available everywhere!
Topicals, Faded Brightening Serum, Reduces ...
 
Erica Alexis profile picture
Pricier, non-hydroquinone brightening foam featuring 6% tranexamic acid and nine complementary brightening and soothing ingredients (such as kojic acid, alpha-arbutin, and niacinamide).
Vivatia by Photozyme
 
Erica Alexis profile picture
Pricier, physician created formulation with a proprietary plant-based ingredient in addition to Kojic Acid, Rumex Occidentalis Extract, Alpha-arbutin and Nonapeptide-1.
Pigment Correct | Natural skin brightening serum
 
Erica Alexis profile picture
Popular, affordable, Korean cream that includes Arbutin, Tranexamic Acid, Niacinamide, Glutathione, Glycerin, Arginine, Allantoin, Adenosine. Fan Fav!
TOSOWOONG Arbutin 7% + Tranexamic Acid 4% Cream
 
Erica Alexis profile picture
Budget serum that includes Arbutin, Tranexamic Acid, Niacinamide, Glutathione, Glycerin, Arginine, Allantoin, Adenosine.
Minimalist Tranexamic Acid Serum + HPA
 
Erica Alexis profile picture
Very pricey novel cream that is only 1 of 2 on the market that contain the proprietary ingredient 7% Cysteamine HCI (to address pigmentation), along with Niacinamide, Shea Butter. This is a great option for those who don't want to use hydroquinone, c...
Cyspera Intensive Pigment Corrector Original
 
Erica Alexis profile picture
Affordable serum that features a unique combination of 5% Tranexamic Acid, 5% Kojic Acid, 2% Alpha Arbutin, Niacinamide, Hyaluronic Acid, Vitamin C, Glutathione, and Natural Fruit AHA.
QUEEN 7-in-1 Super Serum – 5% Tranexamic Acid
 
Erica Alexis profile picture
Korean Discoloration Serum that features Niacinamide, Glutathione, 3% Tranexamic Acid, and NAG.
COSRX - The Alpha-Arbutin 2 Discoloration Care Serum
 
Erica Alexis profile picture
Very budget 10% tranexamic acid serum that also includes Niacinamide, Kojic Acid, Arbutin. Great starter serum for dark spot treatments then progress to something stronger.
ANAI RUI 10% Tranexamic Acid Serum 1.05oz
 
Erica Alexis profile picture
This product is the gold standard for treatment of discoloration but requires a prescription. Please use with caution under physician supervision as it can have side effects. Be sure to cycle off after no more than 8-12 weeks of use to give skin a br...
HYDROQUINONE 4 % CREAM
 
Erica Alexis profile picture
ScriptDerm has a 6% hydroquinone formulation. This product is the gold standard for treatment of discoloration but requires a prescription. Please use with caution under physician supervision as it can have side effects. Be sure to cycle off after no...
ScriptDerm
 
Erica Alexis profile picture
This product is a hydroquinone-free pre-cleanse wash-off treatment designed to visibly fade stubborn hyperpigmentation, melasma, and uneven skin tone. It is the other product that contains 5% Cysteamine, 1% Niacinamide & Vitamin E
HyperCorrect™ Intense Fading Cream
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Erica Alexis profile picture
The only product on my list with Melasyl. Best at addressing general sun spots, post-acne marks, age spots. Not as good as tranexamic acid at lightening melasma & other heat/hormonally induced pigment.
Mela B3 Dark Spot Serum With Melasyl™ + Niacinamide