Here's the core of my setup. The Line 6 Helix LT is pretty much all you need.
If I don't want to use my headphones, I'll be using these!
If you want to replicate the visual quality and simplicity of my setup, here's all the equipment that I use to set my stage.
The Line 6 Helix LT creates the majority of my tones, but I'll also sometimes use various pedals to further create the sound that I want to make.