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Heartburn, GERD & Acid Reflux Relief People Rely On

Purple Star emoji 17 items
As someone who’s dealt with GERD for years, I put this list together with options for daily control, fast flare-up relief, and easy chewables—grouped so it’s simple to find what you need.
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Start here if heartburn happens often

Best for daily control and frequent symptoms
 
Tamara S profile picture
I carry this with me everywhere! It gives me a fast relief from heartburn or acid reflux. 💊 Key ingredient: Famotidine ⏳ When to take: 30 min before meals or at the first sign of heartburn.
1. Kirkland Signature Acid Controller
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Tamara S profile picture
Provides a long-lasting relief from frequent heartburn and acid reflux. I occasionally take omeprazole too and it does work wonders! 💊 Key ingredient: Omeprazole ⏳ When to take: Once daily in the morning before meals for best results.
2. Prilosec OTC Acid Reducer
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Tamara S profile picture
This one also delivers consistent relief by reducing acid at the source. 💊 Key ingredient: Esomeprazole ⏳ When to take: Once daily, usually in the morning before food for ongoing relief from frequent heartburn.
3. Nexium 24HR Acid Reducer & Heartburn Relief Capsules
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Tamara S profile picture
Controls stubborn heartburn when taken daily! Often compared to name brands, with similar lasting results. 💊 Key ingredient: Omeprazole ⏳ When to take: Once daily in the morning, before eating.
4. Equate Omeprazole Delayed Release Tablets
 
Tamara S profile picture
Trusted by thousands, this H2 blocker stops acid in its tracks and provides hours of relief. 💊 Key ingredient: Famotidine ⏳ When to take: 30 min before meals or as needed for heartburn prevention.
5. Pepcid AC Maximum Strength Acid Reducer
 
Tamara S profile picture
A reliable H2 blocker that reduces acid production and helps prevent heartburn when taken before trigger foods. 💊 Key ingredient: Famotidine ⏳ When to take: 30–60 min before meals or at first sign of symptoms.
6. Zantac 360 Maximum Strength Tablets
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Tamara S profile picture
CVS is well-reviewed for delivering quick relief, with many users saying it tastes better than typical antacids. 💊 Key ingredient: Aluminum Hydroxide + Magnesium Carbonate ⏳ When to take: After meals or when heartburn or gas discomfort starts.
7. CVS Health Extra Strength Heartburn Relief
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Fast relief for flare-ups & heavy meals

When heartburn or reflux hits suddenly
 
Tamara S profile picture
This chewable antacid quickly neutralizes stomach acid and helps keep acid down for hours, making it a reliable choice for acid indigestion. 💊 Key ingredients: Magnesium Hydroxide + Aluminum Hydroxide ⏳ When to take: Right after meals or any tim...
1. Gaviscon Extra Strength Antacid
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Tamara S profile picture
Offers a fast and soothing relief for heartburn, acid reflux and gas discomfort, with a liquid formula that many find gentler and more effective than hard chewables. 💊 Key ingredient: Alumunium Hydroxide + Magnesium Hydroxide + Simethicone ⏳ When ...
2. Mylanta Maximum Strength Liquid Antacid
 
Tamara S profile picture
Consistently rated for relief from nausea, heartburn, indigestion, upset stomach, and diarrhea. It coats and soothes the stomach when digestion feels off. 💊 Key ingredient: Bismuth Subsalicylate ⏳ When to take: After meals or anytime you feel any ki...
3. Pepto Bismol Ultra
 
Tamara S profile picture
Ideal if your reflux comes with bloating! This works fast to ease both acid indigestion and gas pressure. 💊 Key ingredient: Calcium carbonate + Simethicone ⏳ When to take: Post-meals or any time needed.
4. Alka-Seltzer Heartburn & Gas Relief
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Tamara S profile picture
Another chewable must-have for bloating! Offers a fast relief from both heartburn and gas. Many say it works quickly and tastes better than chalky antacids. 💊 Key ingredient: Calcium Carbonate + Simethicone ⏳ When to take: After meals or whenever he...
5. Equate Extra Strength Heartburn & Gas Chews
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Chewables & easy, on-the-go relief

Portable and quick neutralizing options
 
Tamara S profile picture
A classic go-to problem solver. Perfect for sudden heartburn or sour stomach on the go. 💊 Key ingredient: Calcium Carbonate ⏳ When to take: Anytime heartburn strikes, especially after meals.
1. Tums Ultra Strength Chewable Antacid
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Tamara S profile picture
Another good option with solid relief. Works effectively and taste good, easing heartburn or upset stomach right away. 💊 Key ingredient: Calcium Carbonate + Magnesium Hydroxide ⏳ When to take: After eating or whenever heartburn or acid indigestion s...
2. Rolaids Extra Strength Chewable Antacid
 
Tamara S profile picture
Currently taking this myself! I love how quick it is for instant relief as it calms my stomach in just 20 minutes and the pain doesn't come back at all. 💊 Key ingredient: Calcium Carbonate ⏳ When to take: Right after meals or whenever heartburn stri...
3. Kirkland Antacid Chewable Tablets
 
Tamara S profile picture
Chewables to soothe heartburn, acid indigestion, and upsets stomach. It works fast and just so easy to take when symptoms hit. 💊 Key ingredient: Aluminum Hydroxide + Magnesium Hydroxide + Simethicone ⏳ When to take: After meals or whenever heartburn...
4. Gelusil Chewable Tablets
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Tamara S profile picture
Helps neutralize acid while supporting digestion, making it ideal for post-meal discomfort. 💊 Key ingredients: Calcium Carbonate + digestive enzyme blend ⏳ When to take: During or right after meals.
5. NOW Supplements: Acid Relief with Enzymes