The key to being comfortable on an airplane flight is to be prepared with essentials.
I've tried several different personal item bags over the years. Some good some not so good, right now I'm happy using a good quality, stylish back pack that has straps that fit over my carry on luggage. This makes it easy to carry either on my shoulders or on the luggage if I'm too tired to pack it through the airport.
Packing cubes, some love them and some people don't. Personally, I do like them as they keep my clothing and items well organized.
Yes, snacks are essentials on a long flight, lol!